Helicobacter pylori infection: Clinical, Endoscopic and Pathological findings in Iranian children
نویسندگان
1 Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
2 Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran
3 Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
4 Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
5 Department of pediatrics, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
6 Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
7 Department of pediatric pathology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
8 Department of pediatrics, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
9 Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
doi
10.22038/ijp.2014.2839چکیده
Background: Helicobacter pylori (H.pylori) infection has an important role in promoting gastrointestinal disease in human. It may be acquired early in life, particularly in developing countries. The aim of this study is to evaluate the association between H.pylori infection and clinical manifestations in Iranian children.Materials and Methods: In this retrospective, cross-sectional study, H. pylori status was assessed by pathological examination of gastric biopsy in symptomatic children. A total of 266 patients were diagnosed as infected by H. pylori, compared with 268 uninfected patients matched by age and sex. Reported symptoms, endoscopic and pathological findings in the two groups were analyzed using chi square test. The limit of statistical significance was set at P
