Synthesis of 2-Amino-4H-chromene Derivatives under Solvent-Free Condition Using MOF-5
نویسندگان
1 Department of Chemistry, Payame Noor University, PO Box 19395‑4697, Tehran, Iran
2 Department of Chemistry, Payame Noor University, PO Box 19395‑4697, Tehran, Iran
3 Department of Chemistry, Payame Noor University, PO Box 19395‑4697, Tehran, Iran
4 Department of Chemistry, Ayatollah Alozma Borujerdi University, Borujerd, Iran
doi
10.22034/chemm.2018.149048.1089چکیده
MOF-5 has been employed as a powerful catalyst for the preparation of 2-amino-4H-chromene. A wide variety of aromatic aldehydes was condensed with malononitrile and 2-naphthol under mild and solvent-free conditions in the presence of the trace amount of catalyst. A variety of 2-amino-4H-chromene can be obtained in good to excellent yield up to 95% in relatively short time reaction and easy workup.
