The Effect of Vitamin C on Ischemia-Reperfusion Injury: A Systematic Review
نویسندگان
1 Student Research Committee, Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Biology, Payam Noor University of Tehran, Tehran, Iran
3 Department of Nursing, School of Nursing, Larestan University of Medical Sciences, Larestan, Iran
4 Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran
5 Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
6 Student Research Committee, Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran
7 Department of Nursing, School of Nursing, Larestan University of Medical Sciences, Larestan, Iran
8 Student Research Committee, Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran
9 Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran
doi
http://dx.doi.org/10.18502/jimc.v7i2.15033چکیده
AbstractIschemia is one of the most common injuries that is usually caused by reduced blood flow to the tissues. Following this incident, the tissue becomes deficient in oxygen and nutrients, and energy production in the affected cells stops, eventually leading to cell damage, but there is also evidence that restoring blood flow to ischemic tissues can lead to extra tissue damage known as Ischemia Reperfusion Injury (IRI). In this study, we reviewed the relationship between vitamin C intake and ischemia/reperfusion injury to investigate the relationship between vitamin C intake and ischemia/reperfusion injury. The keywords “Vitamin C” or “Ascorbic Acid” and “Ischemic” or “Ischemia” and “Reperfusion” were used in this search. The results show that vitamin C has a positive effect on ischemia treatment in the renal tissue, brain, liver, intestine, lung, ovary, pancreas, and skin.
