Exploration of Antioxidant and Anti-inflammatory Activities in Various Parts of Thunbergia fragrans
نویسندگان
1 Department of Chemistry, GITAM School of Science, GITAM Deemed to Be University, Visakhapatnam–530045, Andhra Pradesh, India
2 Department of Chemistry, GITAM School of Science, GITAM Deemed to Be University, Visakhapatnam–530045, Andhra Pradesh, India
doi
10.48309/ajgc.2026.559072.1875چکیده
Oxidation and inflammation are key contributors to chronic diseases such as cancer, cardiovascular disorders, and neurodegeneration. Reactive oxygen species (ROS) cause cellular damage, while chronic inflammation can worsen health outcomes. Antioxidants, though protective against ROS, may have adverse effects when excessively supplemented. This research highlights the importance of natural sources for the extraction of Thunbergia fragrans, a medicinal plant, was studied for its antioxidant and anti-inflammatory properties using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and membrane stabilization assays. Methanol extracts of both leaf and stem showed strong bioactivity (51.63% and 60.32%, respectively), with the leaf extracts nearing the efficacy of diclofenac, the standard anti-inflammatory drug. In contrast, aqueous extracts showed lower activity (79.26), underscoring the role of methanol (97.6) in extracting bioactive compounds. These findings suggest that Thunbergia fragrans is a promising source of natural therapeutic agents. Further research is needed to isolate and characterize the specific compounds responsible for the observed effects.
