One-pot route to nitriles from aldehyde and hydroxylamine hydrochloride on silica-gel
نویسندگان
1 Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal, India
2 Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal, India
doi
10.22034/ajgc.2018.62809چکیده
A green and facile methodology for the synthesis of nitrile has been established from the corresponding aldehydes and hydroxylamine hydrochloride on silica-gel in hot condition. The protocol is equally effective for aliphatic as well as aromatic aldehydes, and has wide range of functional group tolerance. In addition, this methodology is solvent-free, inexpensive, environmental friendly and involves simple work-up process.
