Benzofuroxans as Promising Biocides for Aerobic and Anaerobic Bacteria in Oil and Gas Wastewater Systems
نویسندگان
1 Laboratory of Engineering Profile “Physical and Chemical Methods of Analysis”, Korkyt Ata Kyzylorda University, Kyzylorda, Kazakhstan
2 Department of Chemistry of Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Astana, Kazakhstan
3 Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia
4 Laboratory of Engineering Profile “Physical and Chemical Methods of Analysis”, Korkyt Ata Kyzylorda University, Kyzylorda, Kazakhstan
5 Department of Chemistry of Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Astana, Kazakhstan
6 Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia
7 Laboratory of Engineering Profile “Physical and Chemical Methods of Analysis”, Korkyt Ata Kyzylorda University, Kyzylorda, Kazakhstan
8 Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russia
doi
10.48309/chemm.2025.541585.2000چکیده
To date, the use of classical antibacterial purification schemes in the oil and gas industry is under threat due to the frequent resistance of bacteria to a limited number of biocidal treatment programs. In this regard, the potential of synthetic molecules as biocidal agents is being actively studied worldwide. In this study, benzofuroxans were considered for rational control of microbial contamination in industry, for which derivatives a wide range of antimicrobial activity are currently known, particularly against multidrug-resistant strains. Previously, these compounds with morpholine fragments and a fragment of N-dimethylpropylamine demonstrated the highest cytotoxic activity, correlating well with their ability to inhibit the glycolysis process in tumor cells. Water-soluble salts based on them showed good effectiveness in the pre-sowing treatment of crop seeds, and in some cases, the seed treatment with these salts led not only to improved seed germination, but also to the suppression of microflora growth. Using a panel of tests, the ability of benzofuroxan with the morpholine fragment 4b to significantly reduce the levels of aerobic and anaerobic bacteria was revealed, which encourages its further study as a biocide. Thus, the results indicate the significant potential of benzofuroxans with amine groups for use in the oil and gas industry for wastewater treatment.
