Novel Voltammetric Sensor Based on Ionic Liquid and Co-MOF/MWCNTs Nanostructure: Simple and Sensitive Electrochemical Determination of Daunorubicin
نویسندگان
1 Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran
2 Department of Chemistry, Payame Noor University, Tehran, Iran
3 Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran Iran
4 Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran
5 Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
6 Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
doi
10.48309/chemm.2025.523625.1958چکیده
A novel electrochemical sensor based on carbon paste electrode (CPE) modified with ionic liquid (IL) and nanostructure of cobalt-2-amino-1,4-benzenedicarboxylic acid metal-organic framework (Co-BDC-NH2 MOF) and multi-walled carbon nanotubes (MWCNTs) has been designed and applied for voltammetric determination of daunorubicin. The electrochemical analysis of daunorubicin was performed using cyclic voltammetry (CV) studies, chronoamperometry investigations, and differential pulse voltammetry (DPV) measurements. Due to the improved electron transfer rate at the surface of Co-BDC-NH2 MOF/MWCNTs/ILCPE, the redox peak currents of daunorubicin were higher than other CPEs. From DPV measurements, the Co-BDC-NH2 MOF/MWCNTs/ILCPE-based electrochemical sensing platform detected daunorubicin in the range of 0.008 µM to 340.0 µM, with the limit of detection (LOD) for daunorubicin being 0.003 µM. Furthermore, the developed sensing platform was efficiently used for the analysis of daunorubicin injection with recoveries in the range of 97.8% to 104.0% and relative standard deviations (RSDs) less than 3.3%.
