Micro Spectrophotometric Determination and Cloud Point Extraction of Aspirin with Iron (III) in Pure Form and Pharmaceutical Drugs
نویسندگان
1 Chemistry Department, College of Science for Women, University of Baghdad, Jadiyriah, Baghdad, Iraq
2 Biology Department, College of Science for Women, University of Baghdad, Jadiyriah, Baghdad, Iraq
3 Al-Hussein Military Hospital, Baghdad, Iraq
4 Chemistry Department, College of Science for Women, University of Baghdad, Jadiyriah, Baghdad, Iraq
5 Chemistry Department, College of Science for Women, University of Baghdad, Jadiyriah, Baghdad, Iraq
doi
10.22034/chemm.2022.332256.1449چکیده
Cloud-point extraction and molecular spectrophotometry in tandem was developed and suggested as a method for detecting aspirin and iron (III) ions in pharmaceutical. In a dilute acidic medium, aspirin interacted with Fe(III) ions to produce a brightly colored [Fe(III)-aspirin] complex, which was originally as a mediated extractant, extracted into Triton X-114 micelles, then determined by spectrophotometry at a wavelength maximum of 527 nm. For target analytes, all experimental variables were previously adjusted to accomplish this purpose. The results showed that pre-concentration factors of 80 for aspirin resulted in a detection limit of 0.23 g mL-1 having a linear range of (5-120) gmL-1 (r= 0.9998). For aspirin, a mean recovery percentage of 98. ± 1.09% was recorded, with precision (RSD %) ranging from 0.04-0.66 %.
