KCC-1: An Effective and Green heterogeneous Catalyst for the Synthesis of Pyrido[2,3-d:5,6-d′]dipyrimidine Derivatives
نویسندگان
1 Department of Chemistry, Qom Branch, Islamic Azad University, Qom, I. R. Iran
2 Department of Chemistry, Qom Branch, Islamic Azad University, Qom, P.O. Box 3749
3 Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
doi
10.22036/org.chem.2024.487724.1359چکیده
This work reports the synthesis of pyrido[2,3-d:5,6-d']dipyrimidines using KCC-1 filamentous silica nanoparticles. Pyridopyrimidine compounds are noted for their diverse chemical properties, including antibacterial, antioxidant, and anticancer activities, making them valuable for various industrial applications such as pharmaceuticals, agriculture, and materials science. The synthesis was performed under solvent-free conditions, yielding acceptable results. The nanocatalyst was produced in three steps and characterized using techniques like N2 adsorption-desorption, Brunauer-Emmett-Teller (BET), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and transmission electron microscopy (TEM). The reusability test of KCC-1 demonstrated that the catalyst could be reused multiple times.
