Nucleated Red Blood Cell in Premature Rupture of Membranes
نویسندگان
1 Department of Obstetrics and Gynecology, Reproductive Health Research Center, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
2 Department of Pediatric, Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
3 Department of Pediatric, Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
4 Department of Molecular and cellular Biology, Faculty of Sciences, Guilan University, Rasht, Iran
5 Department of Obstetrics and Gynecology, Reproductive Health Research Center, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
6 Department of Obstetrics and Gynecology, Reproductive Health Research Center, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
7 Department of Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
8 Department of Obstetrics and Gynecology, Reproductive Health Research Center, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
9 Department of Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
doi
10.24200/jogcr.11.7.664چکیده
Background & Objective: Premature Rupture of Membranes (PROM) refers to the rupture of the amniotic sac before the spontaneous onset of labor after the 37th week of gestation. An increase in Nucleated Red Blood Cells (NRBCs) has been observed in infants born following prolonged PROM. This study was conducted with aim to investigate the relationship between the duration of PROM and the NRBC count in the umbilical cord blood of term neonates. Materials & Methods: This cross-sectional analytical study was conducted on term neonates born via cesarean section or vaginal delivery at Al-Zahra Educational and Medical Center in Rasht. Within the first hour after birth, 5 mL of umbilical vein blood was collected to measure the NRBC count per 100 White Blood Cells (WBCs) and the absolute NRBC count. Data were analyzed using IBM SPSS software (version 22). P<0.05 was considered statistically significant. Results: A total of 45 mothers and their infants were included in the study. The mean maternal age was 29.26±6.67 years, the mean duration of PROM was 4.69±0.5 hours, and the mean NRBC percentage was 1.35±2.12%. No significant association was found between the duration of PROM and NRBC count (P=0.451). Conclusion: The present study did not show a significant association between the duration of PROM and the percentage of NRBC in the cord blood of term infants born at our center. Therefore, NRBC counts may not serve as a reliable clinical marker for PROM duration in low-risk term pregnancies.
