Tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives using isonicotinic acid as an efficient catalyst

نویسندگان

1 Sayyed Jamaleddin Asadabadi University, Asadabad, 6541861841, I. R. Iran

2 Sayyed Jamaleddin Asadabadi University, Asadabad, 6541861841, I. R. Iran

3 Sayyed Jamaleddin Asadabadi University, Asadabad, 6541861841, I. R. Iran

doi
10.33945/SAMI/PCBR.2019.2.2.3
چکیده

In this work, we have reported the preparation of pyrano[2,3-d]pyrimidine dione derivatives by the tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives at the presence of isonicotinic acid as an efficient organocatalyst.