Vaginal Adenosis in Two Patients with No History of Diethylstilbestrol: A Case Report
نویسندگان
1 Department of Obstetrics and Gynecology, Fellow of Gynecology Oncology, Women’s Health Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2 Medical Student, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3 Medical Student, Faculty of Medicine, Szeged University of Medical Sciences, Szeged, Hungary
4 Associate professor, Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
doi
10.30699/jogcr.5.4.175چکیده
Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis in female fetus. DES has been reported rarely with no history of fetal use.Case Presentation: In this article, we report two vaginal adenosis patients with no history of DES during pregnancy. There was no vaginal cancer in the follow-up of the patients.Conclusion: Vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.
