Efficient Synthesis of Bis(3-Methylphenyl)Sulfoxide Aza Macrocycles from a Bis(3-Methylphenyl)Sulfoxide Diester and Diamine Derivatives
نویسندگان
1 Department of Basic Sciences, Farhangian University, Tehran, Iran
2 Young Researchers Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran
3 Department of Mathematics and Statistics, University of Guelph, Guelph ON N1G 2W1, Canada
doi
10.22034/jaoc.2022.154822چکیده
Some bis(3-methylphenyl)sulfoxide aza macrocycles (3–8) were synthesized in high yields based on the conventional methods of the reaction of corresponding bis(3-methylphenyl)sulfoxide diester and diamines in refluxing methanol. Bis(3-methylphenyl)sulfoxide diester was synthesized from the reaction of 2-[(2-hydroxy-5-methylphenyl)sulfinyl]-4-methylphenol and methyl chloroacetate. The structures of these compounds were confirmed using IR, 1H NMR, 13C NMR and Mass spectroscopy.
