Iodine‐DMSO Catalyzed Aromatization of Polysubstituted Cyclohexanone derivatives; An Efficient Methods for the Synthesis of Polyfunctionized Biaryls Derivatives

نویسندگان
Gaikwad, Milind V. ID 1
Lokhande, Pradeep D. ID 2
Gaikwad, Sunil V. ID 3

1 Department Of Chemistry, Dr. D. Y. Patil A.C.S. College, Pimpri, Savitribai Phule Pune University Pune- 411018, India

2 Department of Chemistry, Centre for Advanced Research, Savitribai Phule Pune University, Pune 411007, India

3 Department of Chemistry, Centre for Advanced Research, Savitribai Phule Pune University, Pune 411007, India

doi
10.22034/jaoc.2021.128538
چکیده

We have developed a simple method for the regioselective aromatization of Polysubstituted Cyclohexanone derivatives in the presence of iodine (25 mol %), Pd/C (10Mol%) in dimethyl sulfoxide at 90 °C. , afforded functionalized biphenyls with at least one phenolic hydroxyl in moderate to very good yields. The present protocol contains a cheap catalyst, easy work up, normal reaction conditions, and high selectivity.

کلیدواژه‌ها
Molecular iodine, DMSO, Pd/C, Biaryl phenol, multi substituted cyclohexanone