The Translation and Cross-Cultural Adaptation of The Persian Version of The WERF EPHect Endometriosis Patient Questionnaire: A Cross-Sectional Study
نویسندگان
1 Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
2 Breast Disease Research Center (BDRC), Tehran University of Medical Sciences, Tehran, Iran
3 Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
4 Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
5 Nursing Care Research Center, Clinical Sciences Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
6 Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran
doi
10.22074/ijfs.2025.2035263.1728چکیده
Background: The World Endometriosis Research Foundation (WERF) Endometriosis Phenome and BiobankingHarmonisation Project (EPHect) aims to facilitate international research on endometriosis by developinga standardized questionnaire. This study focuses on translating and validating the Persian version of the endometriosispatient questionnaire (EPQ), ensuring cultural compatibility and reliability for future studies inthe region.Materials and Methods: In this cross-sectional study, a total of 37 women aged between 18 and 45 years who wereassessed for endometriosis through diagnostic sonography or laparoscopy, or were suffering from symptoms suchas dysmenorrhea, dyspareunia, pelvic pain not associated with menstruation lasting more than six months, wereevaluated. The evaluation took place from May 2021 to December 2023. The research methodology was structuredinto two phases: translation and cross-cultural adaptation, followed by cross-cultural validation. The Persian versionof the WERF EPHect was translated and adapted in accordance with established guidelines. Content validitywas evaluated by six experts in the relevant fields, while face validity was assessed qualitatively by seven participants.To determine the reliability of the final version of the Persian questionnaire, 30 patients diagnosed withendometriosis completed it on two separate occasions that were two weeks apart, with the repeatability of eachquestion analyzed using Kappa statistics.Results: The translated questionnaire was administered to 30 patients diagnosed with endometriosis, with an averagecompletion time of 55 minutes. Final modifications to the questionnaire were made to align with the Iranianculture, incorporating feedback from specialists and study participants. Overall, the findings suggest that the Persianversion demonstrates both validity and reliability in medical and cultural aspects.Conclusion: The recent study demonstrated that the Persian version of the WERF-EPHect questionnaire is bothvalid and reliable, with cultural relevance. Additional validation studies conducted in various languages will helpeliminate language and cultural disparities, facilitating collaborative, large-scale, prospective international researchon endometriosis.
