فهرست نشریات علمی دسترسی آزاد ایران

Background: The role of laparoscopy and hysteroscopy in managing unexplained infertility (UI) is debatable because ofthe improved success rate of assisted reproductive technologies (ART). This study aims to assess the findings of laparoscopyand hysteroscopy in selected women diagnosed with UI to determine the frequency of such pathological conditionsin order to manage them properly.Materials and Methods: The current cross-sectional study was conducted on 96 women who attended an infertilityclinic at the educational hospitals of Isfahan University of Medical Sciences from March 2018 to February 2020. Theparticipants had one or more of the following conditions: had failed to conceive after 2-3 cycles of ovulation inductionwith clomiphene citrate and intrauterine insemination (IUI), had a history of pelvic infection, pelvic surgery, or ectopicpregnancy (EP). Laparoscopy and hysteroscopic findings were recorded for all participants.Results: Fifty-nine (61.4%) women had primary infertility, while 37 (38.6%) suffered from secondary infertility. In patientswith primary and secondary infertility, 42.3 and 43.2% had laparoscopic abnormalities, respectively. Additionally,33.8 and 21.6% of the participants had hysteroscopic abnormalities in the primary and secondary groups, respectively.The most common findings in the two groups of infertility who had done laparoscopy were endometriosis (21.8%,P=0.201) followed by tubal pathology (13.5%, P=0.952). Also, the most common intrauterine pathology found in bothgroups were uterine septum (7.2%, P=0.753) and endometritis (6.2%, P=0.241).Conclusion: Based on the findings of this study, laparoscopy is recommended in UI after three failed IUI and ovarianstimulation, a history of pelvic pain, pelvic surgery, or pelvic infection; however, it seems that further investigation isrequired to recommend universal hysteroscopy to all women with UI. Nonetheless, it is still emphasized that regionalpractice in one's local settings may also be effective concerning the prevalence of these pathologies.