Nonlocal Interactions in DNA Molecules at Nano-Scale
نویسندگان
1 Department of Physics,Sharif University of Technology
2 Department of Physics,Sharif University of Technology
doi
چکیده
In this paper, we try to explain the origin of the anomalous elastic behavior of nanometersized DNA molecules, which has been observed in all-atom molecular dynamic simulations [A.K. Mazur, Biophys. J. 2006]. It is shown that this anomalous behavior is a consequence of nonlocal interactions between DNA base pairs and the intrinsic curvature of DNA. A nonlocal harmonic elastic rod model is proposed, which can successfully describe the elastic behavior of short DNA molecules.