Nonlocal Interactions in DNA Molecules at Nano-Scale

نویسندگان

1 Department of Physics,Sharif University of Technology

2 Department of Physics,Sharif University of Technology

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چکیده

In this paper, we try to explain the origin of the anomalous elastic behavior of nanometersized DNA molecules, which has been observed in all-atom molecular dynamic simulations [A.K. Mazur, Biophys. J. 2006]. It is shown that this anomalous behavior is a consequence of nonlocal interactions between DNA base pairs and the intrinsic curvature of DNA. A nonlocal harmonic elastic rod model is proposed, which can successfully describe the elastic behavior of short DNA molecules.

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