Electrochemical Assessment of EC and ECE Mechanisms for Caffeic Acid in the Presence of Aromatic Amines
نویسندگان
1 Faculty of Chemistry, Bu-Ali Sina University, Hamedan 65178-38683, Iran
2 Department of Toxicology and Pharmacology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
3 Faculty of Chemistry, Bu-Ali Sina University, Hamedan 65178-38683, Iran
4 Faculty of Chemistry, Bu-Ali Sina University, Hamedan 65178-38683, Iran
doi
10.22036/abcr.2020.206920.1425چکیده
In this work, electrochemical behavior of Caffeic Acid (CA) in absence and presence of aromatic amines such as 4-amino-1,3-Dimethyluracil (4A-DMU), p-toluidine (p-TI), and Sulfacetamide (SA) have been performed by cyclic voltammetry technique in water (sodium acetate, c = 0.15 M)/ethanol (80:20, v/v) mixture. In this way, the effect of different parameters such as concentration and scan rate indicated that the oxidation mechanism of caffeic acid (CA) in the presence of aromatic amines can be EC and ECE. At the working electrode surface, Caffeic Acid (CA) oxidized to correponding o-benzoquinone (CAOX) with two electrons and two protons process. In the following, the Michael-type addition reaction has occurred between o-benzoquinone and aromatic amines. In the second cycle, a new oxidation peak appears in negative potentials than Caffeic Acid (CA) oxidation peak because of the electron-donating properties of amines. Cyclic voltammetry technique can recognize chemical and electrochemical processes in solution and electrode surface, respectively.
