Hemophagocytic lymphohistiocytosis in a patient with systemic lupus erythematous

نویسندگان
Sadeghi, Abdolrahim ID 1
Bashiri, Hamidreza ID 2
Soltani, Hamidreza ID 3
Owlia, Mohammad Bagher ID 4

1 Division of Radiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Rheumatology Department, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

3 Rheumatology Department, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

4 Division of Rheumatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

doi
10.32592/RR.2022.7.4.107
چکیده

Hemophagocytic lymphohistiocytosis (HLH), is a disorder seen more often in children and is life-threatening in terms of over- activation of macrophages, and T cells resulting in cytokine storm. HLH can be familial or secondary to infections,malignancy, immunosuppression, and autoimmune conditions, such as systemic lupus erythematosus (SLE). Here, we report a 10-year old female with previously diagnosed SLE who hospitalized because of fever and pancytopenia.

کلیدواژه‌ها
Systemic lupus erythematosus, Hemophagocytic lymphohistiocytosis (HLH), Cytokine Storm, pancytopenia