Experimental and Insilico Studies on Anti-Microbial Activity of 𝑃. 𝑁𝑖𝑔𝑟𝑒𝑠𝑐𝑒𝑛𝑠 Leaves
نویسندگان
1 Industrial Chemistry Programme, Bowen University, PMB 284, Iwo, Osun State, Nigeria
2 Good Health and Wellbeing Research Clusters (SDG 03), Bowen University, PMB 284, Iwo, Nigeria
3 Department of Science Laboratory Technology, Federal Polytechnic, Ayede, Oyo State, Nigeria
4 Department of Chemical Sciences, Fountain University, Osogbo, Osun State, Nigeria
5 Department of Science Laboratory Technology, Federal Polytechnic, Ayede, Oyo State, Nigeria
6 Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Nigeria
7 Industrial Chemistry Programme, Bowen University, PMB 284, Iwo, Osun State, Nigeria
8 Industrial Chemistry Programme, Bowen University, PMB 284, Iwo, Osun State, Nigeria
doi
10.48309/ajca.2025.473491.1641چکیده
The study was aimed at assessing the phytochemical composition and antibacterial efficacy of Parquetina nigrescens leaves against particular pathogenic microorganisms. In this work, N-Hexane, chloroform, and methanol were used to extract the Parquetina nigrescens. The phytochemical components of the extracts were examined and investigations into the extracts' antibacterial effects against S. pneumoniae, A. baumanii, P. areuginosa, and E. coli were also conducted. The results of the phytochemical examination showed that the extracts included possess various amounts of saponins, tannins, flavonoids, anthraquinones, and alkaloids. As a result of the presence of many phytochemicals, the results of the phytochemical screening suggested that P. nigrescens may have various biological applications. Parquetina nigrescens may be a powerful antibacterial agent, according to the findings of the antimicrobial activities. In addition, the antimicrobial susceptibility test (AST) revealed that Parquetina nigrescens extracts had high potentials in comparison to the control. Moreover, the results of this study suggested that Parquetina nigrescens may hold promise for the creation of effective pharmaceuticals.
