A Recent Concept of Importance: Click Chemistry
نویسندگان
1 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India
2 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India
3 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India
4 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India
5 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India
6 Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India
doi
10.48309/pcbr.2024.461262.1361چکیده
Barry Sharp Lester invented "click chemistry." He won the 2022 Nobel. Click Chemistry has many advantages. Click chemistry has shaped several fields of contemporary chemistry since its inception. Click chemistry has helped us understand and prepare complex molecules. This review examines click response importance. The Huisgen 1,3-dipolar cycloaddition technique produces 1,4-disubstituted 1,2,3-triazoles from azode and terminal alkyne. This discipline is also rapidly expanding in research and development. This paper provides a quick review of CC and its many uses. CuI frequently employs azide-alkyne cycloaddition since it is a powerful change agent. According to research and review studies, generation-wise click chemistry with the Cu(I) catalyst facilitates coupling processes. Click reaction types and groups can be formed from alkynes, cyclooctynes, and azides. This study covers click chemistry and its applications in drug discovery, click chemistry-assisted steroid substitution, the Metal-Free Click Reaction, drug production, and three-dimensional bio-printing. We also examined Click Chemistry's pros and cons and advantages.
