Synthesis of Functionalized Dihydropyrimidothiazinoquinoline Derivatives via Reaction of 3-(Chloromethyl)-2-chloroquinolines and 2-Thioxo-2,3-dihydropyrimidin-4(1H)-one

نویسندگان

1 Chemistry Department, Faculty of Physics and Chemistry, Alzahra University, Vanak, 1993893973 Tehran, Iran

2 Chemistry Department, Faculty of Physics and Chemistry, Alzahra University, Vanak, 1993893973 Tehran, Iran

3 Chemistry Department, Faculty of Physics and Chemistry, Alzahra University, Vanak, 1993893973 Tehran, Iran

doi
10.22036/org.chem.2020.214359.1227
چکیده

An efficient method for the synthesis of novel dihydropyrimidothiazinoquinoline derivatives through the reaction of 2-chloro-3-(chloromethyl)quinolines and 2-thioxo-2,3-dihydropyrimidin-4(1H)-one in the presence of K2CO3 is demonstrated.