A review on analgesic and anti-inflammatory activities of various piperazinyl containing pyridazine derivatives
نویسندگان
1 Department of Pharmacy, Himalayan Institute of Pharmacy and Research, Dehradun, (Uttarakhand), 248007, India
2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, PO Box 840, Saudi Arabia
3 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, PO Box 840, Saudi Arabia
doi
10.33945/SAMI/PCBR.2020.2.1چکیده
Most currently used nonsteroidal anti-inflammatory drugs (NSAIDs) have restrictions for therapeutic use since they cause gastrointestinal and renal side effects that are undividable from their pharmacological activities. In this review various piperazinyl containing pyridazine derivatives have been studied for their analgesic and anti-inflammatory activities and their side effects. Therefore, the synthesis of new compounds devoid of such side effects has become an important goal for medicinal chemists.
