Caro's Acid-Silica Gel Catalyzed Regioselective Ring Opening of Epoxides with Indoles and Imidazoles under Solvent-Free Conditions
نویسندگان
1 Department of Physics and Chemistry, Alzahra University, Tehran,P.O. Box 1993891176, Iran
2 Department of Physics and Chemistry, Alzahra University, Tehran,P.O. Box 1993891176, Iran
3 Department of Physics and Chemistry, Alzahra University, Tehran,P.O. Box 1993891176, Iran
4 Department of Physics and Chemistry, Alzahra University, Tehran,P.O. Box 1993891176, Iran
doi
10.29088/sami/AJCA.2018.1.16چکیده
An efficient and facile procedure has been developed for the ring opening of epoxides with nitrogen heterocycles such as indole and imidazole in the presence of Caro's acid-silica gel (CA-SiO2) as catalyst in solventless system. The reactions were administered underneath Solvent-free conditions. The current methodology offers many benefits like good yields, easy procedure, simple work-up and ecofriendly reaction condition. The catalyst is well ready, stable and economical underneath the reaction conditions.
