فهرست نشریات علمی دسترسی آزاد ایران

Nanotechnology has revolutionized biomedical applications by enabling advancements in drug delivery, diagnostics, imaging, and regenerative medicine. Green synthesis of nanoparticles, an eco-friendly alternative to conventional chemical and physical methods, utilizes biological sources such as plant extracts, microorganisms, algae, and fungi for nanoparticle production. These green-synthesized nanoparticles offer biocompatibility, reduced toxicity, and enhanced functionality, making them promising candidates for biomedical use. A key component in sustainable nanotechnology is nanoinformatics, which integrates computational tools, machine learning, and predictive modeling to optimize nanomaterial design, assess toxicity, and enhance regulatory compliance. Databases like caNanoLab, eNanoMapper, and the Nanomaterial Registry facilitate data sharing and standardization, accelerating research and innovation. Biomedical applications of green-synthesized nanoparticles include targeted drug delivery, antimicrobial and anticancer therapies, biosensing, imaging, wound healing, and tissue engineering. These applications demonstrate their potential to improve therapeutic efficacy, reduce side effects, and enable personalized medicine. Despite their benefits, challenges such as standardization, reproducibility, and regulatory concerns must be addressed to ensure their widespread adoption. This review highlights the convergence of biological source-based green synthesis with nanoinformatics as a powerful approach for developing next-generation, sustainable nanotechnologies in healthcare. Future advancements in nanoparticle-enabled therapies and wearable biosensors will further emphasize the pivotal role of biological sources in shaping the future of biomedical nanotechnology. By overcoming current limitations and fostering interdisciplinary collaborations, sustainable nanotechnology will continue to drive safer, more efficient, and environmentally friendly biomedical innovations.