Biomaterial-based ZnO nanoparticles synthesis using phaleria macrocarpa Extract for antibacterial applications
نویسندگان
1 Department of Biotechnology Graphic Era (Deemed to be University), Dehradun, Uttarakhand, India
2 School of Applied and Life Sciences Uttaranchal University, Dehradun, 248007-Uttarakhand, India
3 School of Applied and Life Sciences Uttaranchal University, Dehradun, 248007-Uttarakhand, India
4 Taqgene Training and Research Institute, Dehradun, Uttarakhand-248007, India
5 School of Applied and Life Sciences Uttaranchal University, Dehradun, 248007-Uttarakhand, India
6 School of Applied and Life Sciences Uttaranchal University, Dehradun, 248007-Uttarakhand, India
7 School of Applied and Life Sciences Uttaranchal University, Dehradun, 248007-Uttarakhand, India
8 Department of Biotechnology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, 248002, India
doi
10.22036/ncr.2025.531887.1497چکیده
This study presents the green synthesis of ZnO nanoparticles using Phaleria macrocarpa fruit extract and evaluates their antibacterial properties. The synthesis process utilizes the fruit extract as a natural reducing and stabilizing agent, obviating the need for hazardous chemicals. To characterize the synthesized ZnO NPs, X-ray diffraction (XRD), scanning electron microscopy (SEM), and UV-visible spectroscopy were used; UV-Vis showed peak absorption at 360 nm and confirmed the synthesis of ZnO nanoparticles. XRD analysis revealed sharp and narrow peaks, signifing the high crystallinity of hexagonal-phase nanoparticles. The spherical shape and clump-like formation of the ZnO NPs were demonstrated by SEM analysis at the nanoscale. The green-synthesized ZnO NPs' antibacterial efficacy against a few selected pathogenic microbes was evaluated. According to the findings, ZnO NPs have the potential to be effective antibacterial agents. This green synthesis method uses the fruit extract of Phaleria macrocarpa, providing an environmentally friendly and sustainable way to produce ZnO NPs with potential uses in food preservation, water purification, and medical treatments. This study highlights the importance of green nanotechnology in creating environmentally friendly and efficient nanomaterials for a range of uses.
