Organometallic Nanoparticulate Delivery: Synthesis, Properties, and Applications
نویسندگان
1 Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Pallavaram, Chennai 600 117, India
2 Department of Pharmacy, University College of Technology, Osmania University, Amberpet, Hyderabad, Telangana 500007, India fAnalytical Scientist, Piramal Pharma, Pennsylvania, United States
3 Department of Pharmaceutical Analysis, MB School of Pharmaceutical Sciences, Mohan Babu University (Erstwhile Sree Vidyaniketan College of Pharmacy) Tirupati, India
4 Vishwakarma University School of Pharmacy Pune-48 Maharashtra India
5 Department of Pharmaceutics, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, India
6 Department of Pharmaceutical Chemistry, Anurag Pharmacy College, Ananthagiri, kodad, suryapet-508206, Telangana, India
7 Department of Chemistry, Lincoln University College, Malaysia
8 Analytical Scientist, Piramal Pharma, Pennsylvania, United States
doi
10.48309/jaoc.2025.506438.1269چکیده
Organometallic nanoparticles (ONPs) are a widespread family of nanomaterials with enormous biomedical, catalytic, and electronic potential. These nanoparticles, characterized by metal-carbon bonds, exhibit various physicochemical properties, including tuneable shape and surface functionalization, and also enhanced optical, electrical, and magnetic behaviours. In this review, an in-depth discussion of ONP preparation methodologies, including chemical, physical, and environmentally friendly processes, and a comparative evaluation of their strengths and weaknesses are discussed. The physicochemical and architectural properties of ONPs, including shape, surface chemistry, stability, and functionalization, have been discussed in detail with a strong emphasis on them. The biomedical potential of ONPs, including drug delivery, bio-imaging, antimicrobial therapy, and bio-sensing, has been critically discussed in detail. Future trends, including improvements in preparation, approval, and commercialization, are also discussed in this review. As nanotechnology continues to grow, with the growing demand for nanotechnology-related innovation, ONPs have enormous potential to revolutionize a range of scientific and technological industries.
