فهرست نشریات علمی دسترسی آزاد ایران

Introduction: The duration of anesthesia and analgesia is reduced in drug addict patients who undergo surgery with intraspinal anesthesia. Methods: This study was a double-blind clinical trial on 68 patients who were candidates for elective orthopedic surgeries of the lower limbs under spinal anesthesia. patients into 2 groups using random numbers table; Intervention (a group of addicted people who received intrathecal marcaine together with fentanyl for spinal anesthesia) and control (a group of addicted people who received only intrathecal marcaine for spinal anesthesia) were divided. Hemodynamic symptoms (mean arterial pressure, heart rate, percentage of arterial oxygen saturation) and nausea and vomiting were measured in both groups. Result: The average mean arterial pressure of patients in both control and intervention groups was not significantly different from each other (P-Value = 0.152). The number of heartbeats per minute of the patients was significantly lower in the intervention group (P-Value < 0.001). The mean percentage of arterial oxygen saturation was not significantly different between the two groups (P-Value = 0.571). The use and non-use of fentanyl has no effect on the incidence of nausea and vomiting (P-Value = 0.259). Conclusion: Based on the results of the present study, the use of intrathecal fentanyl in patients with opium abuse disorder undergoing orthopedic surgery of the lower limbs causes slight changes in mean arterial pressure with a significant decrease in heart rate in these patients.