Phytoconstituent-Based Green Synthesis of Nanoparticles: Sources and Biomedical Applications in Cancer Therapy
نویسندگان
1 Department of Pharmacy, University College of Technology, Osmania University, Amberpet, Hyderabad, Telangana 500007, India
2 Department of Pharmaceutical Analysis, MB School of Pharmaceutical Sciences, Mohan Babu University (Erstwhile Sree Vidyaniketan College of Pharmacy) Tirupati, India
3 Department of Chemistry, Raffles University, Neemrana, Alwar, Rajasthan 301705, India
4 Department of Pharmaceutical Analysis, Annamacharya College of Pharmacy, Rajampet-516126, Andhra Pradesh, India
5 Principal Scientist, Cerevel Therapeutics, 222 Jacobs St. Suite 200, Boston, Massachusetts 02141, USA
6 Vishwakarma University School of Pharmacy Pune-48 Maharashtra India
7 Department of Chemistry, Raffles University, Neemrana, Alwar, Rajasthan 301705, India
8 Department of Pharmaceutics, Seven Hills College of Pharmacy (Autonomous), Venkatramapuram, Tirupati, Andhra Pradesh-517561, India
doi
10.48309/AJGC.2025.501113.1669چکیده
The plant-based green manufacturing of nanoparticles has transformed the medical industry, with nano-textures and nano-medicine representing the forthcoming revolution in this rapidly expanding domain. The concepts and techniques of green synthesis were examined, with emphasis on the generation of nanoparticles from plant phytochemicals. Unlike the methods currently used, green synthesis eradicates toxic by-products and minimizes energy consumption, making it a safer option for large-scale applications. The use of diverse plant sources in nanoparticle synthesis, including medicinal plants, edible plants, algae, and other plant derivatives, shows great potential for synthesizing biocompatible nanoparticles with unique physicochemical properties. The biomedical applications of plant-derived nanoparticles in cancer therapy are taken into account, as well as how they increase therapeutic efficacy, target specificity, and reduce side effects. These nanoparticles have promising novel ways of delivering drugs, imaging, or inhibiting tumor progression through a variety of mechanisms. Future prospects are studied, advocating multidisciplinary research and technological developments to fully harness the promise of green-synthesized nanoparticles. This approach can pave the way for breakthroughs in nano-medicine by tackling existing issues and creating new opportunities. Ultimately, plant-based green synthesis represents a potential and sustainable method for nanoparticle production with significant implications for cancer treatment and other medicinal uses. This ecologically aware approach aligns seamlessly with Global Sustainability Goals and represents a significant advancement in modern medical care.
