An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones
نویسندگان
1 Department of Chemistry, Faculty of Nano and Bio Science and Technology, Persian Gulf University, Bushehr 75169, Iran
2 Department of Chemistry, Payame Noor University, PO Box 19395-3697 Tehran, Iran
doi
10.48309/ajgc.2024.457824.1508چکیده
An effectual eco-friendly protocol for the construction of 4,6-diarylpyrimidin-2(1H)-ones has been described through a solvent-free one-pot multi-component reaction. The condensation of urea, aryl aldehydes, and acetophenones in the Me3SiCl presence produced 4,6-diarylpyrimidin-2(1H)-ones in high yields and relatively short times. In the reported protocols, a catalyst has been used beside Me3SiCl. However, in our protocol, there was no need to utilize a catalyst.
