A green synthesis of isoquinolines using Ru(II)/peg-400 as homogeneous recyclable catalyst via C-H/N-N bond activation
نویسندگان
1 Department of Chemistry, Shri Muktanand Mahavidyalaya, Gangapur,Dist. Aurangabad MS, India
2 Department of Chemistry, L. B. S. Mahavidyalaya, Dharmabad, Dist. Nanded, MS, India
3 Department of Chemistry, L. B. S. Mahavidyalaya, Dharmabad, Dist. Nanded, MS, India
4 Department of Chemistry, L. B. S. Mahavidyalaya, Dharmabad, Dist. Nanded, MS, India
5 Department of Chemistry, L. B. S. Mahavidyalaya, Dharmabad, Dist. Nanded, MS, India
doi
10.22034/AJGC/2020.2.4چکیده
A novel and green synthesis of 1-phenyl isoquinoline derivatives has been developed using [Ru(p-cymene)Cl2]2, as a homogeneous recyclable catalyst, with Cu(OAc)2 and AgSbF6 as oxidant and additive respectively, in PEG-400 biodegradable and green solvent via C-H/N-N functionalization of 1-(diphenylmethylene) hydrazine and aryl substituted acetylene. This protocol gives a simple extraction procedure, biodegradable and green solvent, high atom economy, reusable catalytic system and wide substrate scope with high yield of the product for the synthesis of isoquinoline derivatives.
