Intravenous Iron Sucrose Versus Oral Ferrous Fumarate for the Treatment of Iron Deficiency Anemia in Pregnant Women

نویسندگان

1 Department of Obstetric and Gynecological, Medical College, Al-Qadisiyah University, Diwaniya, Iraq

doi
10.30699/jogcr.9.2.212
چکیده

Background & Objective: The aim of the current study was comparison of the effectiveness of intravenous iron sucrose versus oral ferrous fumarate for the treatment of iron deficiency anemia during pregnancy.Materials & Methods: This is a prospective randomized clinical trial enrolling 100 pregnant women with iron deficiency anemia who visited the Al-diwaniya Educational Hospital for maternity and children from October 2022 to July 2023 whose ferritin level was less than 15 ng/ml and Hb level was between 70-10.9g/L. They were treated with either intravenous iron sucrose or oral ferrous fumarate for four weeks.  Formerly, patients were allocated into two groups. The patients in the group I received ferrous fumarate pills, each enclosed with elemental Iron 100 mg.  Group II got 100 ml of 0.9% NaCl containing a dose of iron sucrose dissolved in it and calculated by a specific equation. After four weeks, serum ferritin and hemoglobin levels were assessed, and the adverse effects were also monitored.Results: Comparing hemoglobin levels produces a substantial pre- and post-treatment difference (P=0.001). Serum Ferritin Level harvest significant differences pre- and post-treatment (P=0.001). The post-treatment comparison of the two groups showed a significant difference in each group (P= 0.001).Conclusion: Maternal iron reserves are more effectively increased by intravenous ferrous sucrose than by oral ferrous fumarate.