Synthesis of Polyfunctionalized Pyrroles by a PPh3-Promoted Condensation Reaction Between Ammonium Acetate, Dialkyl Acetylenedicarboxylate and Arylglyoxals

نویسندگان

1 Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, I.R. IRAN

2 Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, I.R. IRAN

doi
10.30492/ijcce.2017.24034
چکیده

A simple and efficient synthesis of some polyfunctionalized pyrrole derivatives by a triphenylphosphine-promoted condensation reaction between dialkyl acetylenedicarboxylates, arylglyoxals, and ammonium acetate is described. This present  method carries several advantages, such as good yields, a simple procedure, non-hazardous reaction conditions and starting from easily accessible substrates