Chemoenzymatic Enantioselective Formal Synthesis of (-)-Gephyrotoxin-223

نویسندگان
Mohammadi Ziarani, Ghodsi ID 1
Chenevert, R. ID 2
Badiei, Ali Reza ID 3

1 Department of Chemistry, Alzahra University, Tehran, I.R. IRAN

2 Departement de Chimie, Faculte des sciences et de genie, Universite Laval, Quebec, G1K 7P4, CANADA

3 Department of Chemistry, University of Tehran, Tehran, I.R. IRAN

doi
10.30492/ijcce.2006.8096
چکیده

(-)-Gephyrotoxin-223 was formally synthesized from chiral synthon 1 which has been chemoenzymatically synthesized  in the presence  of Candida Antartica lipase.        

کلیدواژه‌ها
Gephyrotoxin, Indolizidine, Chemoenzymatic, Candida Antartica Lipse, Alkaloids, Desymmetrization