Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles
نویسندگان
1 Department of Chemistry, Faculty of Pharmacy, The Medical Science University of Tehran, Zip code 14174, Tehran, I.R. IRAN
2 Department of Chemistry, Faculty of Pharmacy, The Medical Science University of Tehran, Zip code 14174, Tehran, I.R. IRAN
doi
10.30492/ijcce.1998.10300چکیده
The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl-2-isoxazolines.