Review of Current Diagnostics Developed for COVID-19
نویسندگان
1 Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
2 Izmir Biomedicine and Genome Center, Balcova 35330, Izmir, Turkey
3 Medical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, 89195-999, Yazd, Iran.
4 Medical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, 89195-999, Yazd, Iran.
5 Biotechnology Department, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6 Livogen Pharmed, Research and Innovation Center, Tehran, Iran
7 Department of Medical Oncology, Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
8 Department of Analytical Chemistry, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Turkey
doi
10.22036/abcr.2021.271340.1593چکیده
COVID-19 emerged in 2019 as a pandemic that affected the world in many aspects and it have been the biggest challenge for many countries in the past year. Due to the lack of approved treatment methods for the disease, and more importantly, to inhibit its spread, the critical task is to detect it fast and reliable. Many research groups and companies have been developing different methods and products for the diagnosis of COVID-19. Each method has advantages and disadvantages, while rapid, inexpensive, and high-throughput detection methods are needed. In this regard, significant progress has been achieved so far. In this article, we reviewed in-vitro Diagnostics (IVD) and Commercial Kits in three main categories including real-time reverse transcription-polymerase chain reaction kits, serology-based tests, and point-of-care diagnostic tests. In addition, familiarizing with coronavirus and its detection methods, genome study, Cell entrance and antigenicity, and Specimen, Lab Biosafety, and Authorization of Medical Devices for COVID-19 were discussed.
