A Systematic Review on the Role of Silver Nanoparticles in Treatment of Oral Cancer
نویسندگان
1 Division of Dental Biomaterials, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran
2 Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
3 Faculty of Health and Life Sciences, INTI International University, Nilai 71800, Malaysia
4 Advanced Dental Science and Technology Research Center, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran
5 Department of Prosthodontics, ZA Dental College, Aligarh Muslim University, Aligarh 202002, India
6 Department of Prosthodontics, ZA Dental College, Aligarh Muslim University, Aligarh 202002, India
7 Department of Prosthodontics, ZA Dental College, Aligarh Muslim University, Aligarh 202002, India
doi
10.48309/chemm.2025.522423.1959چکیده
Oral cancer is a deadly and serious threat to humanity. Unfortunately, despite the existence of many clinical methods in the diagnosis and treatment of oral cancer, conventional treatment methods have been criticized due to many side effects and insufficient damage to the target tumors. The breakthrough of nanotechnology in the field of medicine in recent years has led to the upgrading of traditional treatments and the elimination of shortcomings of conventional cancer diagnosis and treatment. Recently, silver nanoparticles (AgNPs) have gained the most attention in the treatment of oral cancer due to their diverse properties, including ease of preparation, biological activities, antifungal, antiviral, anti-inflammatory, and especially antibacterial and anticancer properties. Nowadays, AgNPs synthesized using plant extracts are playing a crucial role in nanotechnology, economical, suitability for mass production, safety, rapidity, and single-step processes. In this review, we first summarize the current applications of AgNPs in the diagnosis and treatment of oral cancer. This work aims to provide a literature review of studies on AgNPs and their potential applications, particularly in the context of oral cancer therapy. This systematic review summarizes current evidence on the use of silver nanoparticles in oral cancer diagnosis and treatment.
