Complexation of Ag(I) with 8-Hydroxyquinoline: Synthesis, Spectral Studies and Antibacterial Activities
نویسندگان
1 Chemistry Department, Faculty of Science, University of Benghazi, Benghazi, Libya
2 Chemistry Department, Faculty of Science, Misurata University, Misurata, Libya
3 Medical Laboratory Department, Faculty of Medical Technology, Misurata University, Misurata, Libya
4 Department of Food Industries, Faculty of Agriculture, Misurata University, Misurata, Libya
5 Chemistry Department, Faculty of Science, Misurata University, Misurata, Libya
doi
10.22034/ajca.2022.322123.1294چکیده
In the present study, silver complex with 8-hydroxyquinoline (8-HQ) was synthesized and characterized by FT IR and UV-VIS spectroscopic methods. The stoichiometric ratio, molar absorptivity, and formation constant were evaluated using UV-VIS spectrophotometric method. Both oxygen and nitrogen atoms from 8-HQ were included in the complex formation as stated by the spectral data. The UV-VIS spectrophotometric data indicated the formation of (1:1) complex with a formation constant of 4.2x108. Also, the antimicrobial effects of the ligand and the complex were examined in vitro. The diffusion style was used to investigate the antimicrobial activity on some chosen gram-positive and gram-negative bacteria. The ligand and its metal complex possessed antibacterial activity for particular bacteria such as Staphylococcus aureus and Proteus spp. The antimicrobial activity of the complex was higher with gram-negative bacteria. Meanwhile, the 8-HQ was found to have an appreciably higher capability to inhibit the growth of the gram-positive bacteria.
