A Short Synthesis of Carbazole Alkaloids Murrayanine and Mukonine

نویسندگان
Kadam, Shuddhodan N. ID 1
Gaikwad, Milind V. ID 2
Acharya, Ashok P. ID 3
Dawane, Bhaskar S. ID 4
Kamble, Rahul D. ID 5
Abhore, Ajay N. ID 6
Gaikwad, Sunil V. ID 7
Hese, Shrikant V ID 8

1 Department of Chemistry, VidnyanMahavidhyalaya, Sangola, Solapur (MS) India -413307

2 Department of Chemistry, D.Y. Patil ACS College Pimpri, affiliated, Savitribai Phule Pune University, Pune (MS) India-411018

3 Department of chemistry Mudhoji College, Phaltan- Satara(MS) India-415523

4 School of Chemical Sciences, SRTM University, Nanded (MS) India -431606

5 Department of Chemistry, Amruteshwar ACS, College, Vinzar, Pune (MS) India-412213

6 Department of Chemistry, PDVP College, Tasgaon, Sangli (MS) India -416312

7 Department of Chemistry, Savitribai Phule Pune University, Pune (MS) India-411007

8 D.D. Bhoyar College of Arts and Science Mouda, Nagpur, 441104, MS, India

doi
10.22034/chemm.2021.131552
چکیده

The short, easy and total synthesis of Murrayanine (1),  Mukonine (2), carbazole alkaloids were elaborated, based on a regioselective buchwald coupling of methyl 4-bromo-3-methoxybenzoate  with aniline and successive transformation into the corrsponding carbazole alkaloids by  oxidative coupling followed by cyclization of the phenyl and aryl rings.  

کلیدواژه‌ها
Carbazole Alkaloids, Mukonine, Murrayanine, Buchard coupling