Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus
نویسندگان
1 Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
2 Rheumatology Department, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
3 Rheumatology Department, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
4 Rheumatology Department, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
doi
10.22631/rr.2020.69997.1102چکیده
Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novelcoronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.
