Evaluation of Thimerosal on the Potency and Stability of Inactivated Animal Rabies Vaccine

نویسندگان
Alireza Gholami ID 1
Mohammad Chehrazi ID 2
Saeed Jodairi Eslami ID 3
Ali Moradi-Joshaghan ID 4
Farzaneh Ahmadnejad ID 5
Nargess Miandehi ID 6
Zohreh Parhizkar ID 7
Bahram Roshanaei ID 8

1 Human Rabies Vaccine Laboratory, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.

2 School of Public Health, Tehran University of Medical Science, Tehran, Iran

3 Viral Vaccines Production Department, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.

4 Viral Vaccines Production Department, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.

5 Viral Vaccines Production Department, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran 09383473270

6 1Viral Vaccines Production Department, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran

7 Viral Vaccines Production Department, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.

8 Viral Vaccines Production Department, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.

doi
10.22037/aab.v10i3.26363
چکیده

Thimerosal is used as a preservative in Rabies vaccine. This study aimed at comparing potency and stability of inactivated animal rabies vaccine with and without thimerosal. Therefore, two groups of rabies vaccine were produced. The results indicated that thimerosal has no deleterious effect on the vaccine; furthermore, its elimination did not influence the potency and stability of the vaccine.

کلیدواژه‌ها
Thimerosal, Potency, Rabies vaccine