فهرست نشریات علمی دسترسی آزاد ایران

Background and Aim: In recent years, the world has witnessed the emergence of CRISPR/Cas-9, a low-cost, accessible, and precise gene-editing biotechnology that can target and modify specific segments of DNA responsible for particular traits or disorders without harming other regions. Unlike genetically modified organisms (GMOs), this technology avoids many of their potential ethical and biological challenges. Its ability to revolutionize agricultural practices-by improving crop yields and quality through targeted genetic modifications-necessitates a jurisprudential analysis to establish ethical and legal frameworks governing its application within domestic contexts. Materials and Methods: This research is an interdisciplinary study in the fields of biotechnology and Islamic jurisprudence, employing a descriptive-analytical methodology. By reviewing the latest scholarly articles and existing knowledge on CRISPR, it investigates the jurisprudential legitimacy of utilizing this technology to enhance food security in agricultural products. Conclusion: The utilization of CRISPR technology in agriculture does not conflict with the divine purpose of creation and holds the jurisprudential ruling of permissibility among the fivefold Islamic legal classification (aḥkām khamsah taklīfiyyah). Furthermore, it carries the applied ruling of legality. By analyzing principles such as the prohibition of wastefulness (isrāf)-given CRISPR’s role in preventing resource depletion-and its alignment with "strengthening the Islamic system", alongside evaluating arguments from proponents and opponents, this study concludes that its use is permissible and lawful under normal circumstances. In cases of necessity or emergency, however, jurisprudential evidence-such as the obligation to preserve life (ḥifẓ al-nafs), protect societal integrity (ḥifẓ kiyān), and the Quranic injunction "And prepare against them whatever you are able" (Quran 8:60)-as well as the rational precedent of preventive measures, render its application obligatory and legally binding. Therefore, formulating laws and standards for CRISPR must be integrated into the national legislative framework.