Evaluation of Anti-inflammatory Activity of Methanolic Extractof Solanum nigrum(Solanaceae): Anti-inflammatory effect of Solanum nigrumLinn extract
نویسندگان
1 Centre for Advanced Research in Indian System of Medicine, SASTRAUniversity, Thanjavur,Tamilnadu, India
2 School of Pharmaceutical SciencesVels College of Pharmacy, Chennai- 600 035, Tamilnadu, India.
3 PGPCollege of Pharmaceutical Science and Research Institute, NH-7, Namakkal - Karur MainRoad, Namakkal - 637207, Tamilnadu, India
4 Bharathidasan Institute of Technology, Anna University Tiruchrappalli, Tiruchirappalli - 620024, Tamilnadu, India
5 KRS Pallavan College of Pharmacy, Mannur - 602 105, Tamilnadu, India
doi
10.22037/ijps.v5.41210چکیده
The methanolic extract of whole plants of Solanum nigrumL. was investigated for anti-inflammatory activity on the experimental animal models. The methanolic extract at a concentration of 100 mg.kg-1and 200 mg.kg-1, p.o.showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. Anti-inflammatory activity of the tested extract was comparable with that of the standard drug indomethacin (10 mg.kg-1) and cyproheptadine (8mg.kg-1). The results lend support to the traditional use of Solanum nigrumin the treatment of inflammatory diseases
