Preparation and Evaluation of Blood Compatibility of NovelEpoxy-Modified Polyurethanes: Blood compatible polyurethanes
نویسندگان
1 Biomaterial Department, Faculty of Medical Engeneering, Amir Kabir University of Technology,Tehran, Iran
2 Polyurethane Department, Iran Polymer and Petrochemical Institute, Tehran, Iran
3 Medical Physics and BioMedical Engineering Department, School of Medicine, IsfahanUniversity of Medical Sciences, Isfahan, Iran
doi
10.22037/ijps.v4.41059چکیده
In order to prepare polyurethane elastomers with acceptable physical properties and good biocompatibility, novel polyurethane networks were synthesized via curing reaction of epoxy-terminated polyurethane prepolymers (EUPs) with hexamethylene diamine. EUPs were prepared from reaction of glycidol with NCO-terminated polyurethanes (ITPs). ITPs were also synthesized from reaction of one equivalent of either poly(tetramethylene ether)glycol or poly(ethylene glycol) with hexamethylene diisocyanate. Cytotoxcicity and blood compatibility were evaluated.All of the prepared polymers via this novel and simple method showed nontoxic behavior and acceptable blood compatibility.
