Cytotoxic Effects of Five Species of Inula Against Some Tumor Cell Lines: Cytotoxicity of Inula spp

نویسندگان

1 Traditional Medicine and Materia Medica Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran

2 Traditional Medicine and Materia Medica Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran

3 Traditional Medicine and Materia Medica Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran

4 Department of Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

doi
10.22037/ijps.v2.40322
چکیده

The chloroform soluble fractions of ethanolic extracts of five Inula belonging to the Compositae family were evaluated for cytotoxic activity against five different cell lines including CACO2 (human colon adenocarcinoma), MCF7 (human breast adenocarcinoma), HEPG2 (human hepatocellular carcinoma), VERO (green African monkey kidney) and WEHI164 (balb c mouse fibrosarcoma). Cytotoxicity was assessed by MTT assay. Among these five species, Inula oculus christi, exhibited better cytotoxic effects.