Durian: The King of Fruits with Potential Anti-Cancer Properties – A Scoping Review of Current Findings

نویسندگان

1 Department of Agricultural Technology, Faculty of Agriculture, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

2 UPM-MAKNA Cancer Research Laboratory (CANRES), Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

doi
10.22037/aab.v15i1.45906
چکیده

Context: The king of fruits of Southeast Asia, durian, which is rich in bioactive chemicals, has drawn interest due to its possible anticancer effects. Evidence Acquisition: This review paper investigates the latest scientific findings regarding the fruit's potential as an anticancer agent. There are research gaps, especially in the absence of in vivo studies to corroborate the cytotoxic effects of durian extract on different cancer cell lines. Results: In vitro studies have shown these effects on cancer cell lines. The study indicates future directions, including in vivo models, mechanistic investigations, and investigation of combination therapy. It emphasizes the need for more research to clarify the molecular processes behind durian's anticancer properties. Conclusion: By filling these knowledge gaps, durian has the potential to become a valuable natural cancer-fighting agent.

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