Protective Role of α-Pinene in Cuprizone-Induced Multiple Sclerosis in Mice
نویسندگان
1 Division of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran.
2 Graduate student, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran
doi
10.22037/aab.v13i1.38101چکیده
Introduction: It is clamied that α-pinene has properties against Multiple Sclerosis (MS) which is known as demyelination of the neurons. Given that, the aim of this study was to investigate the effect of α-pinene on Cuprizone-induced (CPZ) MS. Materials and Methods: A total of forty C57BL/6 mice were allocated to 4 groups. Mice in group 1 (control) were treated with a normal diet. In group 2, CPZ-induced demyelination was done by chew palate containing .2% (w/w) CPZ for 5 weeks. In group 3, a normal diet was provided and mice were injected with
