فهرست نشریات علمی دسترسی آزاد ایران

Background: Post-cholecystectomy syndrome is one of the most common complications of laparoscopic cholecystectomy. The present study aimed to investigate factors affecting post-cholecystectomy syndrome in laparoscopic cholecystectomy surgery in patients with gallstones. Materials and Methods: In this prospective cohort study, 100 patients with gallstones who underwent laparoscopic cholecystectomy were included. Patients were evaluated and followed up for 6 months using a checklist of possible factors affecting post-cholecystectomy syndrome, including demographic, non-biliary, biliary, and extrabiliary factors. Results: Among the 100 patients participating in this study, 21 (21%) experienced post-cholecystectomy syndrome within 6 months. Higher age (P-value<0.001), male gender (P-value: 0.048), involvement with diabetes (P-value: 0.038), involvement with gastritis (P-value: 0.005), and increased CBD diameter (P-value<0.001) were significantly associated with the occurrence of PCS. Logistic regression analysis revealed that only Helicobacter pylori infection had a significant impact on the incidence of PCS (SE: 1.053, CI95%: 2.592- 160.858, P-value: 0.004), whereas linear regression did not. Conclusion: The results obtained from this study showed that old age, diabetes, Helicobacter pylori infection, male gender, and gastritis are related to the occurrence of post-cholecystectomy syndrome.