Intraventricular Hemorrhage in Term Neonates: Sources, Severity and Outcome
نویسندگان
1 2. Division of Neonatology, Ali-Asghar Children’s Hospital, Iran University of Medical Science, Tehran, Iran
2 3. Pediatrician, Ali-Asghar Children’s Hospital, Iran University of Medical Science, Tehran, Iran
3 1. Department of Pediatric Neurology, Ali-Asghar Children’s Hospital, Iran University of Medical Science, Tehran, Iran
doi
10.22037/ijcn.v9i3.7414چکیده
How to Cite This Article: Afsharkhas L, Khalessi N, Karimi Panah M. Intraventricular Hemorrhage in Term Neonates: Sources, Severity and Outcome. Iran J Child Neurol. Summer 2015;9(3):34-39. AbstractObjectiveIntraventricular hemorrhage (IVH) occurs in preterm infants; however, theoccurrence of this event is less frequent in term neonates. The present studyevaluated clinical characteristics, pathophysiological features, and earlyoutcome of term neonates with IVH in a referral neonatal center in Iran.Materials & MethodsThis study was performed on 30 full-term neonates admitted to the NeonatalIntensive Care Unit (NICU) of Ali-Asghar Hospital, Tehran, Iran betweenMarch 2005 and April 2011. IVH was diagnosed using cranial ultrasonography,or brain magnetic resonance imaging (MRI).ResultsThe mean age at onset of symptoms was 3.9 days. Seizure was the commonestclinical symptoms followed by poor feeding and fever. The sources ofbleeding in the brain were choroid plexus (60%), germinal matrix (20%) andparenchyma (6.7%). Severity of bleeding included 33.3% grade I, 30.0% gradeII, 36.7% grade III to IV. Fifteen (50%) cases had coagulopathy. Twenty-five(83.3%) cases were discharged with a good condition, three (10%) cases werereferred to surgical ward and two cases (6.7%) died in NICU.ConclusionThe main source of IVH in term neonates is choroid plexus; the most commonclinical symptoms include seizure and poor feeding, and one-third of IVHevents are graded as III to IV. Most affected neonates are discharged fromNICU without CNS complication, about 10% need to refer to surgicalinterventions, and death was occurred in a few of neonates.