Relationship between Iron Deficiency Anemia and Febrile Seizures
نویسندگان
1 MD,Pediatric Neurologist, Associate Professor, Tehran University of Medical Sciences, Tehran, Iran
2 Medical students, Baqyiatallah University of Medical Sciences,Tehran, Iran
3 MD,Assistant Professor, Baqyiatallah University of Medical Sciences, Tehran, Iran
4 Medical student, Shahid Beheshti University of Medical Sciences, Tehran,Iran
5 MD,Pediatric Neurologist, Assistant Professor, Baqyiatallah University Medical Sciences, Tehran, Iran
6 Medical students, Baqyiatallah University of Medical Sciences,Tehran, Iran
7 MD,Associate Professor, Baqyiatallah University of Medical Sciences, Tehran, Iran
8 MD,Assistant Professor, Baqyiatallah University of Medical Sciences, Tehran, Iran
doi
10.22037/ijcn.v4i1.1722چکیده
ObjectiveFebrile seizure is the most common convulsive disorder in childhood. The role of iron in metabolism of neurotransmitters and carrying oxygen to the brain suggests the possibility of a relationship between iron deficiency anemia and febrile seizures.The aim of this study was to investigate the relationship between iron deficiency anemia and febrile seizures.Materials & MethodsThis case - control study was performed on 132 cases and 88 controls, aged 9 months to 5 years, from July 2007 to June 2009 in Baqyiatallah Hospital. Patients were selected using simple random sampling. The case group included children with first febrile seizure (core temperature over 38.5˚C during seizure) without a central nervous system infection or an acute brain insult. The control group included children suffering from a febrile illness without seizure. Iron deficiency anemia was defined with one of these laboratory indexes: 1) Hemoglobin (Hb) <10.5mg/dl 2) Plasma ferritin <12ng/dl 3) Mean corpuscular volume (MCV) <70 fl. The data collected from patients were analyzed with SPSS.13 software.ResultsLow plasma ferritin was found in 35 cases (26.5%) compared to 26 controls (29.5%), low Hb level was found in 4 cases (3%) compared to 6 controls (6.8%) and low MCV was found in 5 cases (3.8%) compared to 6 controls (6.8%).There was no significant difference in plasma ferritin , Hb level and MCV indices between the two group.ConclusionConsidering the above-mentioned results, there is no relationship between iron deficiency anemia and febrile seizures.
